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Şefa DSP Dolj a fost depistată pozitiv la SARS-CoV-2 după a doua doză de vaccin. Cum este explicată situaţia

24
1 Feb 2021 09:40:06
Autor: Ana Popescu
Valeria Andreescu, şefa DSP Dolj FOTO Arhiva Adevărul
Valeria Andreescu, şefa DSP Dolj FOTO Arhiva Adevărul

Valeria Andreescu, directorul executiv al Direcţiei de Sănătate Publică Dolj, a fost confirmată pozitiv la trei zile după ce i-a fost administrată a doua doză de vaccin. Soţul, şi el angajat DSP, este în aceeaşi situaţie. La fel şi soacra directoarei.

Valeria Andreescu şi soţul său, inginer la serviciul administrativ al DSP Dolj,  şi-au făcut rapelul pe data 26 ianuarie 2021. Barbatul a fost primul care a început să se simtă rău. Avea temperatură şi alte simptome specifice infectării cu COVID 19.

Cei doi şi-au făcut testul RT-PCR, iar ambii au ieşit pozitivi. În acest moment, Valeria Andreescu şi soţul său se află în izolare. 

Specialiştii din Ministerul Sănătăţii au făcut precizări că astfel de situaţii pot să apară.
 
„Este posibil ca astfel de cazuri să mai apară în perioada următoare, ceea ce nu poate fi interpretat ca un eşec al vaccinării în general, al vaccinării cu produsul dezvoltat de BioNTech/ Pfizer în particular”, se arată pe site-ul Guvernului României.
 
„În primul rând, după cum o arată dovezile din studiile clinice, răspunsul imun ca urmare a vaccinării apare la circa 10-14 zile după prima administrare, iar efectul maxim (răspunsul protector maxim) apare la 7 zile după a doua administrare/ după rapel. Ceea ce înseamnă că se poate produce o infectare cu virusul SARS-CoV-2 după administrarea primei doze, întrucât acea perioadă este considerată perioadă de “fereastră imunologică”, adică perioada când încă nu a apărut răspunsul imun.
 
O altă explicaţie poate fi şi aceea că persoana respectivă, despre care relatează ştirea, era, în momentul vaccinării, fie în perioada de incubaţie, fie deja infectată şi aflată în fază asimptomatică", se mai precizează pe site-ul Guvernului României.
 
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Cum arată echipa lui Voiculescu de la Sănătate: 15 consilieri şi patru secretari de stat. Ultima „achiziţie”, o absolventă de Teologie
 
Controversa Ivermectinei: Rectorul UMF Cluj, specialist în farmacologie, explică efectele medicamentului 

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24 Comentarii

profilatu
1.02.2021, 10:28:11

Astea sunt parerile mele, necalificate. Probabil si in RO ne intereseaza ponderea noii tulpini descoperita de britanici la ei, si celelalte doua, cine stie ce mutanti se mai selectioneaza nestiuti si prin Asia. Britanicii, au testat mai simplu, si mai ieftin cred, din cate inteleg eu(!). Poate ca nu au facut secventiere, poate au folosit doar teste. Au numarat doar cazurile foarte pozitive (cu putine cicluri PCR). Cred ca ar fi suficient pentru a determina raportul dintre diferitele tulpini existent si in RO. Similar s-ar putea cauta si celelalte variante, sudafricana si braziliana. Speculez ca s-ar putea folosi testele astea tip proiectate sa detecteze aceste gene particulare, sau aparatele PCR. [00][11] [00] Dr. J Campbell: "The spike gene [of the new virus] is no longer detected in the current test. Now, this is just fortunate. It just so happened that the test that we're using in the UK, it tests for three parts of the viral genome and, where's a mutation, it doesn't show that bit up. So, you think it might give a false negative, but it doesn't because it tests [positive] for two other parts of the virus. So, if it's the new variant [of the virus] you'll get two positive areas on the antigen test and the spike area [on the test] will be negative. But if it's the old variant [of virus], all three [areas on the test] you will be positive. So, it's actually really easy to tell the difference between the two variants [of virus, prevailing in UK] from the standard antigen polymerase chain reaction test. So, that was quite fortunate, really. And during this transition period, where the UK has been changing from the old variant to the new UK variant, the B.1.1.7 variant, that's essentially given us two groups: the old variant group and the new variant group. And, of course, we can compare and contrast between those groups. So, it's really been a natural experiment, really. So, just fortunate that that's the way it worked out. Unfortunately, that we have the [new] variant, it's been a complete disaster, of course. But that's the way it's worked out which is handy for the research purposes." de la min 1:50, google: youtube Dr. John Campbell New variant causes more symptoms sau click: https://www.youtube.com/watch?v=PrTvpBUdmHI [11] "Swabs are tested for three genes present in the coronavirus: N protein, S protein and ORF1ab. Each swab can have any one, any two or all three genes detected. Positives are those where one or more of these genes is detected in the swab other than tests that are only positive on the S-gene, which is not considered a reliable indicator of the virus if found on its own. The new UK variant of Coronavirus (COVID-19) has genetic changes in the S-gene. This means the S-gene is no longer detected in the current test, and cases that would have previously been positive on all three genes are now positive only on the ORF1ab- and the N-gene (not the S-gene). There are also other reasons why a swab may be positive for only these two genes, including lower viral load in the sample, which is why we have always seen a small percentage of this type of positive result. Absence of the S-gene appears to have become a reliable indicator of the new UK variant from mid-November, based on the higher levels of virus in these type of positives after this date. Prior to that, the data should not be read as being an indicator of the variant. In contrast, the South African variant has an S-gene that is detectable with the current test..." google: Office for National Statistics Coronavirus (COVID-19) Infection Survey, UK: 22 January 2021 sau click: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/22january2021#positive-tests-that-are-compatible-with-the-new-uk-variant Un studiu britanic, inca neverificat, zice ca tratamentul cu plasma convalescenta nu ajuta deloc.[22] Cel putin daca nu e administrata de la inceput, dupa mintea mea(!). Simultan insa, pe ambele maluri, lumea se plange de lipsa plasmei. Se pare ca trebuie administrata devreme, probabil in ordinea prioritatilor, presupun eu(!), cei in varsta si cei cu comorbiditati, supraponderali samd.[33][44][55] Nu stiu la ce moment in tratament a fost administrata plasma convalescenta in studiul respectiv (de tip Randomized Control Trial, mare, britanic). Dar, tinand seama de mortalitate (identica = 18% si la cei tratati cu plasma si la cei tratati cu placebo), asta ar insemna, dupa mine(!), ca au fost inrolati pacienti cu un tablou clinic deja mai avansat, mai grav. Deci, ar parea ca plasma a fost administrata nu chiar de la primirea testului pozitiv. Deci doctorii trebuie sa revada studiul, sa imagineze alte terapii cu plasma data devreme, iar donatorii nu trebuie sa se descurajeze. POTUS a primit din start Regeneron, un anticorp monoclonal de sinteza, care, dupa intelegerea mea(!), functioneaza teoretic dupa acelasi principiu ca si plasma convalescenta. Parerea mea(!) este ca plasma convalescenta a fost administrata compasional, la cazurile deja grave, unde viremia a atins deja niveluri mari, sistemul imunitar a raspuns, dar mai incet decat la altii, uneori fatal de incet, pscienti la care s-au dezvoltat deja anticorpi in sange, poate in concentratie mai mare decat poate crea aportul exterior de anticorpi din plasma convalescenta administrata IV. Dupa ploaie, chepeneag. Era logic de la inceputul pandemiei. Regeneron costa vreo 2000E doza.[66] Dar daca virusul se tot extinde, transforma si perfectioneaza[661], si acesti anticorpi monoclonali, si plasma convalescenta, si vaccinurile, si masurile de distantare etc incep toate sa piarda din eficienta, trebuie reproiectate, asa ca vaccinuri viitoare sunt din ce in ce mai probabile pana virusul este eliminat global, atat intre oameni cat si intre animale [77]. Media ar trebui sa pregateasca populatia pentru aceste posibile/probabile scenarii nu pentru optimism nejustificat fiindca asta ar putea agrava inutil criza [88]. Tinand cont ca imunitatea generata de vaccin poate sa descreasca in timp, ca apar noi variante de virus care au o transmitere si o letalitate mai mari, e probabil ca nici procentul de 70% din populatie necesar pana acum pentru imunitate de turma este deja mic, pe masura ce virusul evolueaza, procentul necesar creste. Asta cere munca de lamurire si solidaritate. Daca nu se atinge procentul necesar, probabil vor tot fi izbucniri locale, cum s-a intamplat in ultimii ani la noi cu rubeola si pojarul. Ar aparea si probleme cu UE, o sa exportam probleme. Exista oricum categorii care vor ramane neprotejate precum copii prea mici sa fie vaccinati, cei cu sistem imunitar slab, HIV, chemoterapie, transplant, batrani. Ma intreb cum vor putea antivaxerii sa se plimbe printre acestia si casnicii lor punandu-i in pericol. Sa pui presiune i-ar face sa se incapataneze si mai tare, e deja chestie de vanitate, daca nu de frica. Si la fermele de animale, poate vor trebui preferati ingrijitori vaccinati, lasand la o parte ca si animalele ar trebui vaccinate in masa, simplu si ieftin. Vaccinurile pentru noile variante sunt deja in dezvoltare calidarea va fi mai rapida, tinand conta ca se introduc doar modificarile survenite la virus.[99] [22] "On the advice of the DMC [,Data Monitoring Committee], recruitment to the convalescent plasma arm of the RECOVERY trial has now closed. The DMC saw no convincing evidence that further recruitment would provide conclusive proof of worthwhile mortality benefit either overall or in any pre-specified subgroup. The DMC reviewed data on patients randomised to convalescent plasma vs. usual care. The preliminary analysis based on 1873 reported deaths among 10,406 randomised patients shows no significant difference in the primary endpoint of 28-day mortality (18% convalescent plasma vs. 18% usual care alone...)" google: youtube Dr. John Campbell Convalescent plasma, no benefit google: recoverytrial RECOVERY trial closes recruitment to convalescent plasma treatment for patients hospitalised with COVID-19 sau click: https://www.youtube.com/watch?v=48FqFqd0MvI&feature=youtu.be https://www.recoverytrial.net/news/statement-from-the-recovery-trial-chief-investigators-15-january-2021-recovery-trial-closes-recruitment-to-convalescent-plasma-treatment-for-patients-hospitalised-with-covid-19 [33] US "We are seeing very new studies come out that suggest that the earlier you give it [plasma to COVID-19 patients], the better it is... We just simply can't keep up. So we need as many of our recovered COVID-19 patients as possible to roll up their sleeves and come in and donate." google: youtube CBS News Dire shortage of convalescent plasma, as cases of COVID-19 surge sau click: https://www.youtube.com/watch?t=48&v=WjFRV7Ma-5U&feature=youtu.be [44] UE: "many doctors would like to use plasma more often ideally giving it to patients in the early stages of the disease when it's likely to work best but the problem is there isn't enough of it" google: youtube DW News Antibody drugs and blood plasma therapy: Livesavers for COVID patients? | COVID-19 Special sau click: https://www.youtube.com/watch?t=110&v=hdQ0AvpBC6A&feature=youtu.be [55] A Fauci: "...monoclonal antibodies and convalescent plasma, since they are giving antibodies to someone who would need a direct antiviral effect of the antibody, it is best to use it early, before individuals actually have had the opportunity to progress. And that's what we're going to be seeing in the future is an attempt to as early as possible get this interventions to the patients..." de la 10:34, google: youtube Dr. Fauci, White House Covid-19 Response Team hold briefing | NBC News sau click: https://www.youtube.com/watch?t=634&v=wVHRiiys1bw&feature=youtu.be [66] Jens Spahn: "Starting next week, the monoclonal antibodies will be used in Germany as the first country in the EU. Initially in university clinics... The federal government has bought 200,000 doses for €400 million... They act like a passive vaccination. Administering these antibodies in the early stages can help high-risk patients avoid a more serious progression..." google: DW Coronavirus: Germany to use new antibody-based drug sau click: https://www.dw.com/en/coronavirus-germany-to-use-new-antibody-based-drug/a-56328493 [661] Dr A Fauci: "...one of the best ways to prevent the further evolution of mutants is to get as many people vaccinated as quickly as possible. And the reason is, viruses don't mutate unless they actively replicate. So, when you have a lot of disease in the community and a lot of infections, the way we, unfortunately, have had in the US over the last several months, then you give the virus a lot more opportunities to mutate. If we can implement our vaccine programs with the vaccines that we currently have and bring the level of virus replication and dynamics in the community to a very low level, the virus will not mutate as efficiently as it does when you have an explosion of infections." de la min 2:37, google: youtube PBS NewsHour Fauci on the efficacy of new vaccines and preparing for coronavirus variants sau click: https://www.youtube.com/watch?t=157&v=RQePJ0rrojQ&feature=youtu.be [77] "working on coronavirus vaccines for mink. The animals have grown sick and died in large numbers from the virus, which they have also passed back to people in mutated form... All members of the weasel family are susceptible to infection and to developing some symptoms and passing on the virus..." google: nytimes The Coronavirus Kills Mink, So They Too May Get a Vaccine sau click: https://www.nytimes.com/2021/01/22/science/covid-mink-vaccine.html [88] Dr P Hotez: "So, the take home message... is nothing changes in the immediate future. You want to go ahead, get your vaccine, get those two doses, but down the line there may be a need for a third immunization, a boost. And if that boost is done, it may be against the South African variant. And, just to keep everybody calm, remember that we thought there was a pretty high likelihood we might have to give a third immunization down the line anyway at some point, because we had no idea about the durability of any protection of any of these vaccines especially the new technology vaccines: do they last for three months, three years, or 30 years? So, everyone was pretty confident we were going to need a third immunization down the line anyway and all we're really saying is that third immunization is going to have to be probably specifically directed against the South African variant. That's the scenario that's looking the most plausible right now, the one we're mostly in discussions with our [American] vaccine and the other vaccine developers are as well." de la min 2:33, google: youtube Dr. Peter Hotez: Researchers Have Been Planning For Virus Variants | The Last Word | MSNBC sau click: https://www.youtube.com/watch?t=152&v=e8UKXXdGRk8&feature=youtu.be [99] Dr S Gottlieb: "...I think we can have them [updated vaccines] in time for the fall [in US]. We need to come up with a regulatory framework that allows the boosters to be licensed on the ability to demonstrate that they can produce antibody levels. And FDA is working on that. They've talked about developing guidance that would allow companies to develop boosters to the existing vaccines that could be licensed just on the basis of proving that in 300 or 400 patients they can induce antibody levels at a sufficient level that are protective against these new variants... The companies have said they're already working on those new boosters... the platforms that the companies use to develop these vaccines, these synthetic platforms, lend themselves to those quick adaptations." de la 4:12, google: youtube Face the Nation Gottlieb says vaccination "should be a backstop" to protect against virus variant sau click: https://www.youtube.com/watch?t=252&v=F1Lf4lbil6g&feature=youtu.be

+1 (3 voturi)
Alfa Omega
1.02.2021, 11:29:28

Simplul nu au trecut 10 de la rapel , asta este s-a infectat inainte ca vaccinul sa aiba efect , dar tot are noroc ca v-a face o forma mai usoara !, Intrebarea este de ce a avut prioritate la vaccin ?

+2 (6 voturi)
Alexandru Preda
1.02.2021, 10:42:12

Faceți ceva cu reclamele astea puturoase, care zac pe conținut!!! Nu pot citi articolul din cauza lor!

+7 (7 voturi)
Taranul Vasile
1.02.2021, 11:17:51

Alexandru Preda AdBlock

+1 (11 voturi)
H David
1.02.2021, 11:28:27

Adevarul e ca e un soi de apa de ploaie, vezi ca israelul a zis ca are eficienta maxim 33%, ei au vaccinat deja 2 milioane, iar de la pfizer astia te cam poti astepta la manareli, avand in vedere ca in fiecare an aproape au luat amenzi uriase pentru ca au platit doctori sa recomande medicamente neeficiente, asa ca te poti baza pe ei pentru eficienta vaccinului, cam ca si pe apa de ploaie, si aia poate ajuta ceva mai ales daca e administrata la unu ce are deja anticorpi

+3 (11 voturi)

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